Description
This course covers different systems of weights and measures required for compounding and dispensing of drugs in pharmacy practice. It is also concerned with all manufacturing formulations aspects, additives, packaging, storage, stability and quality control testing of liquid dosage forms including solutions (aqueous and non-aqueous), colloids, suspensions and emulsions with emphasis on the technology and pharmaceutical rationale fundamental to their design and development. The incompatibilities occurring during formulation are also considered. The course also defines preformulation and the main parameters as polymorphism, crystal size, shape and habit which will affect drug physical and chemical stability.
Program
Bachelor of Pharmacy - PharmD (Clinical Pharmacy)
Objectives
- Knowledge and Understanding
By the end of the course, the students should be able to:
a1. Define liquids, suspensions and emulsions in order to understand their application in different dosage forms.
a2. Illustrate the various techniques used in their preparation.
a3. Identify the basic factors that control their stability.
a4. Enumerate the various additives used in liquids, suspensions and emulsions and their relevance in the manufacture of various dosage forms.
Intellectual Skills
By the end of the course, the students should be able to:
b1. Deduce the methods and techniques that could be applied to prepare liquids, suspensions and emulsions.
b2. Differentiate between the different types of liquids, suspensions and emulsions and the suitability of each type to various dosage forms.
b3. Apply laws related to their stabilization and complexation.
b4. Apply the settling and sedimentation theory
Professional and Practical skills
By the end of the course, the students should be able to:
c1. Prepare dispersed phase pharmaceutical dosage forms (colloids, emulsions and suspensions).
c2. Stabilization of various disperse systems
General and Transferable skills
By the end of the course, the students should be able to:
d.1. Communicate effectively during interactive modules.
d.2. Work under stress within certain limits.
d.3. Verify the skills of self learning using text book and internet.
d.4. Use numeracy and calculation.
